In early 17th century, Schiener used reflection of marbles from the cornea as perhaps the earliest corneal topography.
Placido’s disc was a major advancement in the late 19th century. Placido disc has stood the test of time and the current placido based topographers work on the same principle of assessing the reflection of a concentric set of white rings from the convex anterior surface of the cornea.
Recent advances in the technology use scanning slit methods for assessment of elevation data and incorporation of distortion free scheimpflug photography techniques.
Some important indications of the corneal topography include the following:
1) Refractive surgery:
To screen candidates for normal corneal shape, patterns and ruling out suspicious or keratoconic patterns . Post operatively , topography can help to assess the dioptric change created at corneal level (thus the effective change in the cornea) , ruling out decentred or incomplete ablation , post excimer ectasia or other changes.
2) Keratoconus :
Early screening of keratoconus suspects is one of the most useful roles of topography. Early keratoconus and suspects look normal on slit lamp examination ,and the central keratometry (3 mm) gives only a limited assessment. Therefore topography has become the gold standard in screening keratoconus suspects. In cases with established keratoconus, the role of topography is paramount for monitoring progression and doing a timely collagen cross linking , and in contact lens fitting.
3) Post surgery astigmatism :
Post cataract surgery and post keratoplasty corneal astigmatism can be studied with the topographer and selective suture removal or other interventions can be planned.
4) Surgical planning in cases with astigmatism :
Limbal relaxing incisions and other methods of topography guided incision placement are used by surgeons to reduce post operative astigmatism.
5) Effect of corneal and ocular surface disorders:
Disorders such as pterygium , limbal dermoid , localised corneal scars can cause a change in the corneal topography and thus the monitoring is very useful.
6) Other uses :
Contact lens fitting , incision placement and intrastromal ring placement in keratoconus , monitoring of ocular vs corneal wavefront.
Placido Disc Reflection analysis:
The primary optical aim of cornea is refraction and focusing of the light rays as it acts as a covering lens overall. However , all non-ideal refracting surfaces reflect some light off them. This is the principle used for Purkinje imaging as well in the Placido discs. Placido disc is a device made of concentric rings drawn on a device of a different color. The first refracting surface of the cornea (the tear film –air interface) also acts as convex mirror and reflects back light in a pattern dependent of the corneal pattern. Topographers use this technique to their advantage. Whereas the original placido discs were aimed a qualitative keratoscopy , the videokeratoscope or the topographer uses mathematical formulaes to provide a point to point quantitative gradient of these subtle changes in topography.
Scanning Slit elevation evaluation:
It is one of the elevation based methods for assessment of topography. Multiple complimentary slits are used to perform an assessment of the corneal surface. In the Orbscan , 40 slits (20 each from nasal and temporal side) are projected on the cornea to assess 240 points on each slit. The triangulation between the reference slit beam surface and the reflected beam captured by the camera can be used to analyse the anterior and posterior corneal curvature and the pachymetry.
Scheimpflug based assesment:
The non planar shape of cornea can potentially lead to spurious results and therefore the use of schiempflug principle in corneal imaging is a welcome new change. Theodre Scheimpflug , an Austrian army man worked extensively on a method for correcting ariel distortion in perspective photographs. According to the Scheimpflug principle, when a planar subject is not parallel to the image plane , an oblique tangent can be drawn from the image, object and lens planes, and the point of intersection is called schiempflug intersection. Using this orientation, a careful manipulation of the image plane and the lens plane can however lead to a focused and sharp image on the non parallel object.
Interpretation of a topography printout:
A modern topography printout can be quite daunting for the beginner because of the volumes of data it contains. This is a major shift from the rather simplistic videokeratographs and keratometers.
A stepwise approach is very handy in interpretation.
Step 1 : Correctly identify the patient ,age and the eye.
Step 2 : Look at the quad or multi map option as it gives the best visual comparison of the data.
Step 3: Look at the pseudocolor scale and identify the range and gradient of the values given. Each scan will have a color coding scale for the indices measured. For the absolute topographic map, there will be the absolute dioptric value at that point of the cornea. As we are trained to look at patterns for keratoconus or other corneal abnormalities, a tighter color coding scale may enhance patterns or more lax color coding scale will lead to missing out patterns .
Step 4: On an absolute scale, the green colors are most representative of normative data and thus a quick review of the scan will help. Too much red is almost always abnormal. The scan should now be mentally compared to patterns seen in keratoconus or other suspected corneal disorder. A classical pattern may be picked up easily , however more experience is required for atypical patterns.
Step 5: The next step is to look at the actual numbers on the charts and in the statistics boxes. Numerical overlays show thinning and central corneal thickness, apical keratometry, anterior and posterior corneal elevations and specific details at a point.
Author: Dr. Imran Saleem
Consultant Ophthalmologist & Senior Registrar at Bahawal Victoria Hospital, Bahawalpur